The management of colorectal liver metastases has evolved rapidly over the last decade with the introduction of newer and effective chemotherapies and a redefinition for cure. These range from the philosophical (including the greater awareness of treatment with curative intent), through the practical (more aggressive definition of respectability for cure and the use of more effective chemotherapies for both palliation and as adjuncts to surgery), to the futuristic use of biological strategies (including monoclonal antibodies and gene therapies) and lastly to the pragmatic but equally important issues of health economics (who is going to foot the bill for these increasingly expensive treatment strategies).

"This book addresses the contemporary multidisciplinary management of liver metastases. Throughout the text, experience from the paradigms of colorectal cancer metastases treatment strategies are used to point to new directions in the management of liver metastases from other cancers.The book will be invaluable for surgeons in general surgery, hepatobiliary surgery, upper GI surgery, colorectal surgery, medical and clinical oncologists with an interest in liver tumours, and radiologists with an interest in liver disease."

Radiological Imaging of Liver Metastases.- Biology of Colorectal Cancer Liver Metastases.- Surgery for Colorectal Metastases.- Destructive Therapies for Colorectal Cancer Metastases.- Systemic Therapy for Non-operable Colorectal Cancer Metastases.- Locoregional Chemotherapy for Hepatic Metastasis of Colorectal Cancer.- Oncosurgical Strategies for Unresectable Liver Metastases.- Adjuvant Chemotherapy.- Biologicals for Colorectal Cancer Metastases.- Internal Radiation for the Treatment of Liver Metastases.- Surgical Treatment of Colorectal Liver Metastases in Elderly Patients.- Health-Related Quality of Life and Palliative Care in Colorectal Liver Metastases.- Carcinoid Liver Metastases: The Carcinoid Syndrome.- Gastrointestinal Stromal Tumors.- Surgery for Breast Cancer Liver Metastases.- Liver-Directed Therapy for Metastatic Melanoma to the Liver.- Non-colorectal Gastrointestinal Liver Metastases.